Publications - Douglas A. Cotanche, Ph.D.

Parker, M.A and D.A. Cotanche. The potential use of stem cells for cochlear repair. Audiology & Neuro-Otolology 2004;9:72-80.

Mangiardi, D.A., K.M. Williamson, K.E. May, E.P. Messana, D.C. Mountain and D.A. Cotanche. Progression of Hair Cell Ejection and Molecular Markers of Apoptosis in the Avian Cochlea following Gentamicin Treatment. J. Comp. Neurol. 2004; 475:1-18

Matsui, J.I. and D.A. Cotanche. Sensory Hair Cell Death and Regeneration: Two Halves of the Same Equation. Current Opinion in Otolaryngology & Head and Neck Surgery, 2004, 12:418-425.

Morest, D.K and D.A. Cotanche. Regeneration of the inner ear as a model of neural plasticity. J. Neurosci Res., 2004, 78:455-460.

Roberson, D.W., J.A. Alosi and D.A. Cotanche. Direct transdifferentiation gives rise to the earliest new hair cells in regenerating avian auditory epithelium. J. Neurosci. Res. 2004, 78:461-471.

Wang, H., J. Li, P.L. Follett, D.A. Cotanche, J.J. Volpe and P.A. Rosenberg. 12-Lipoxygenase plays a causal role in cell death caused by glutathione depletion and arachadonic acid in cultured rat oligodendrocytes. Eur. J. Neurosci. 2004, 20:2049-2058.

Parker, MA, JK Anderson, DA Corliss, VE Abraira, R Sidman, KI Park, DA Cotanche, EY Snyder. Expression profile of an operationally-defined neural stem cell clone. J. Exp. Neurol., 2005,194:320-332.

Matsui, J.I., M.A. Parker, B.M. Ryals and D.A. Cotanche. Regeneration and replacement in the vertebrate inner ear. Drug Discovery Today, 2005, 10:1307-1312.

Mangiardi, D.A. and D.A. Cotanche. Mechanisms of aminoglycoside-induced hair cell death. In: P. Steyger and J. Ripper, eds. Volta Review, Washington, DC: AGBell Assoc. 2005; 105: 357-371.

Dai, C.F., D.A. Mangiardi, D.A. Cotanche, and P. S. Steyger. Accumulation of fluorescent gentamicin by vertebrate sensory cells in vivo. Hearing Research 2006; 213:64-78.

Ryals, BM, JI Matsui and DA Cotanche. Regeneration of hair cells. In: C.M. Campbell, ed. Pharmacology and Ototoxicity for Audiologists, Clifton Park, NJ:Thomson Delmar Learning; 2005, in press.

Duncan, LJ, JK Anderson, KE Williamson, DA Mangiardi, JI Matsui, DA Cotanche. Characterization of myosin VI and VIIa distribution through gentamicin-mediated hair cell death and regeneration in the avian cochlea. JCN 2006, in press.

Cotanche, DA, Saunders, JC, Tilney, LG. Hair cell damage produced by acoustic trauma in the chick cochlea. Hearing Res. 1987;25:267-286.

Cotanche, DA. Development of hair cell stereocilia in the avian cochlea. Hearing Res. 1987;28:35-44.

Cotanche, DA. Regeneration of hair cell stereociliary bundles in the chick cochlea following severe acoustic trauma. Hearing Res. 1987;30:181-196.

Cotanche, DA. Regeneration of the tectorial membrane in the chick cochlea following severe acoustic trauma. Hearing Res. 1987;30:197-206.

Schneider, ME, Cotanche, DA, Fambrough, DM, Matschinsky, FM. The cellular distribution of the Na+-K+ ATPase in the chick cochlea. Hearing Res. 1987;31:39-44.

Tilney, LG, Tilney, MS, Cotanche, DA. Actin filaments, stereocilia and hair cells of the bird cochlea V. How the staircase pattern of stereociliary lengths is generated. J. Cell Biol. 1988;106:355-365.

Corwin, JT, Cotanche, DA. Regeneration of sensory hair cells after acoustic trauma. Science 1988;240:1772-1774.

Tilney, LG, Tilney,MS, Cotanche, DA. New observations on the stereocilia of tall and short hair cells of the chicken cochlea. Hearing Res. 1988;37:71-82.

Tilney, MS, Tilney, LG, Stephens, RE, Merte, C, Drenckhahn, D, Cotanche, DA, Bretscher, A. Preliminary biochemical characterization of the stereocilia and cuticular plate of hair cells of the chick cochlea. J. Cell Biol. 1989;109:1711-1723.

Corwin, JT, Cotanche,DA. The development of location-specific hair cell stereocilia in denervated embryonic ears. J. Comp. Neurol.1989; 288:529-537.

Cotanche, DA, Dopyera, CEJ. Effects of acoustic trauma on hair cells and supporting cells in the chick cochlea. Hearing Research 1990;46:29-40.

Shiel, MJ, Cotanche, DA. SEM analysis of the developing tectorial membrane in the chick cochlea. Hearing Research 1990;47:147-158.

Cotanche, DA, Corwin, JT. Stereocilia bundles reorient during hair cell development and regeneration in the chick ear. Hearing Res. 1991;52:379-402.

Stone, JS, Cotanche, DA. Hair cell differentiation in the developing chick cochlea and in embryonic cochlear organ culture. J. Comp. Neurol. 1991;314:614-625.

Cotanche, DA. Video-enhanced DIC images of the noise-damaged and regenerated chick tectorial membrane. Experimental Neurology 1992;115:23-26.

Stone, JS, Cotanche, DA. Synchronization of hair cell regeneration in the chick cochlea following noise damage. J. Cell Science 1992;102:671-680.

Cotanche, DA, Henson, MM, Henson, OW Jr. Contractile proteins in the hyaline cells of the chicken cochlea. J. Comp. Neurol.1992; 324:353-364.

Tilney, LG, Cotanche, DA, Tilney, MS. Actin filaments, stereocilia and hair cells of the bird cochlea VI. How the number and arrangement of stereocilia is determined. Development 1992;116:213-226.

Stone, JS, Cotanche, DA. Identification of the timing of S phase and the patterns of cell proliferation during hair cell regeneration in the chick cochlea. J. Comp. Neurology 1994;341:50-67.

Freeman, DM, Cotanche, DA, Ehsani, F, Weiss, TF. The osmotic response of the isolated tectorial membrane of the chick to isosmotic solutions: Effect of Na+, K+, and Ca2+ concentration. Hearing Research 1994;79:197-215.

Lee, KH, Cotanche, DA. Detection of ß-actin mRNA by RT-PCR in normal and regenerating chicken cochleae. Hearing Res. 1995;87:9-15.

Epstein, JE, Cotanche, DA. Secretion of a new basal layer of tectorial membrane following gentamicin-induced hair cell loss. Hearing Res. 1995;90:31-43.

Cotanche, DA, Messana, EP, Ofsie, MS. Migration of hyaline cells into the chick basilar papilla during severe noise damage. Hearing Res. 1995;91:148-159.

Janas, JD, Cotanche, DA Rubel, EW. Avian cochlear hair cell regeneration: stereological analyses of damage and recovery from a single high dose of gentamicin. Hearing Res. 1995;92:17-29.

Lee, KH, Cotanche, DA. Localization of the hair cell specific protein fimbrin during regeneration in the chicken cochlea. Audiology & Neuro-Otology 1996;1:41-53.

Lee, KH, Cotanche, DA. Potential role of bFGF and retinoic acid in the regeneration of chicken cochlear hair cells. Hearing Res. 1996;94:1-13.

Ofsie, MS, Cotanche, DA Distribution of nerve fibers in the basilar papilla of normal and sound-damaged chick cochleae. J. Comp. Neurol. 1996;370:281-294.

Ofsie, MS, Hennig, AK, Messana, EP, Cotanche, DA. Sound damage and gentamicin treatment produce different patterns of damage to the efferent innervation of the chick cochlea. Hearing Res. 1997;113:207-223.

Hennig, A.K. and D.A. Cotanche. Regeneration of cochlear efferent nerve terminals after gentamicin damage. J. Neurosci 1998;18: 3282-3296.

Fernandes, R., M. Fox, D.A. Cotanche, K. Lennon, and M.A. Kukuruzinska. Confocal imaging of gene expression during hamster salivary gland biogenesis. Ann. NY Acad. Sci. 1998;842:212-216.

Cotanche, D.A. 1999. Can Hair Cells be Made to Regrow After Cochlear Damage? Hearing Loss 1999;20: 19-22.

Fernandes, R.P., Cotanche D.A., Lennon-Hopkins, K., Erkan, F., Menko, A.S., and Kukuruzinska, M.A. 1999. Differential expression of proliferative, cytoskeletal, and adhesive proteins during postnatal development of the hamster submandibular gland. Histochem. Cell Biol. 111: 153-62.

Kruger, R.P., R.J. Goodyear, P.K. Legan, M. Warchol, Y. Raphael, D.A. Cotanche, and G.P. Richardson. The supporting-cell antigen: a receptor-like protein tyrosine phosphatase expressed in the sensory epithelia of the avian inner ear. J. Neurosci. 1999;19: 4815-4827.

Torchinsky, C., E.P. Messana, M. Arsura, and D.A. Cotanche. 1999. Regulation of p27 Kip1 in the avian cochlea during gentamicin mediated hair cell death and regeneration. J. Neurocytol. 1999;28:913-924.

Roberson, D.W., J.A. Alosi, E.P. Messana, and D.A. Cotanche. Effect of violation of the labyrinth on the sensory epithelium in the chick cochlea. Hear. Res. 2000;141: 155-164.

Roberson, D.W., J.A. Alosi, E.P. Messana, A.P. Netter, and D.A. Cotanche. Endotracheal isoflurane anesthesia for chick auditory surgery. Hear. Res. 2000;141: 165-168.

Kenna, M.A., B.-L. Wu, D.A. Cotanche, B. Korf, H. Rehm. Connexin26 mutations in patients with sensorineural hearing loss. Arch Otolaryngol HNS 2001;127:1037-1042.

Roberson, D.W., J.A. Alosi, M. Mercola, D.A. Cotanche. Role of REST in cell fate in normal and regenerating avian auditory epithelium. Hearing Res. 2002;172:62-72.

Matsui, J.I., A. Haque, D. Huss, E.P. Messana, J.A. Alosi, D.W. Roberson, D.A. Cotanche, J.D. Dickman and M.E. Warchol. Hair cell function and survival following aminoglycoside treatment with caspase inhibitors in vivo. J. Neurosci. 2003; 23:6111-6122.

Roberson, D.W., J.A. Alosi and D.A. Cotanche. Direct transdifferentiation gives rise to the earliest new hair cells in regenerating avian auditory epithelium. J. Neurosci. Res. 2003; submitted.

Mangiardi, D.A., K.M. Williamson, K.E. May, E.P. Messana, D.C. Mountain. and D.A. Cotanche. Progression of Hair Cell Ejection and Molecular Markers of Apoptosis in the Avian Cochlea following Gentamicin Treatment. J. Comp. Neurol. 2003; in preparation

Dai, C.F., D.A. Mangiardi, D.A. Cotanche, and P. S. Steyger. Accumulation of fluorescent gentamicin by vertebrate hair cells in vivo. Hearing Research 2003, in preparation.

Wang, H., J. Li, P.L. Follett, D.A. Cotanche, J.J. Volpe and P.A. Rosenberg. 12-Lipoxygenase plays a causal role in cell death caused by glutathione depletion and arachadonic acid in cultured rat oligodendrocytes. J. Neurosci. 2003, in preparation.

Cotanche, D.A., R. Wagner and C. Lechene. Protein Turnover in the Tectorial Membrane of the Normal and Regenerating Avian Cochlea Analyzed by Multiple Imaging Mass Spectrometry (MIMS). Science 2003, in preparation.

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